超重和肥胖患者 24 小时动态心电图监测中心律失常（包括室上性和室性早搏以及其他心电图模式）的患病率
Life
(
IF
3.2
)
Pub Date : 2024-09-09
, DOI:
10.3390/life14091140
Irena Anna Dykiert
1
,
Krzysztof Kraik
2
,
Lidia Jurczenko
2
,
Paweł Gać
3
,
Rafał Poręba
4
,
Małgorzata Poręba
5
Affiliation
Department of Physiology and Pathophysiology, Division of Pathophysiology, Wroclaw Medical University, 50-368 Wrocław, Poland.
Students' Scientific Association of Cardiovascular Diseases Prevention, Wroclaw Medical University, 50-368 Wrocław, Poland.
Department of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, 50-345 Wrocław, Poland.
Department and Clinic of Angiology and Internal Medicine, Wroclaw Medical University, 50-556 Wrocław, Poland.
Department of Paralympic Sport, Wroclaw University of Health and Sport Sciences, 51-617 Wrocław, Poland.
目的：本研究旨在评估超重和肥胖人群中各种心律失常和其他心电图模式的患病率。方法：181 名成年人（90 名女性和 91 名男性）符合纳入实验组的资格。所有参与者的体重指数 (BMI) 均超过 25 kg/m2（98 名患者肥胖，83 名超重）。肥胖组的平均BMI为33.6 kg/m2，所有参与者均为1级肥胖。对照组包括 69 名体重指数正常的个体（56 名女性和 13 名男性）。进行了基本测量，参与者填写了描述其健康状况和生活方式的调查问卷。每个参与者都接受了心电图（ECG）检查和24小时动态心电图检查。结果：与对照患者相比，1 级肥胖患者的室性早搏 (PVB) 和室上性早搏 (SPB) 的平均次数在统计学上显着较高（p = 0.030 和 p = 0.042）。体重与 PVB 之间呈正相关（p = 0.028），体重与 SPB 之间呈正相关（p = 0.028）。此外，BMI 和腰围与 SPB 相关（p = 0.043 和 p = 0.031）。在考虑24小时动态心电图监测的向后逐步多元回归模型中，以SPB为因变量，观察到BMI（特别是肥胖1级）、2型糖尿病和甲状腺疾病表现出最高的回归系数。结论：肥胖，即使是 1 级肥胖，也可能是心电图测试异常更频繁发生的一个因素。
The Prevalence of Arrhythmias, Including Premature Supraventricular and Ventricular Beats and Other Electrocardiographic Patterns, in 24-Hour Holter Monitoring in Patients with Overweight and Obesity
Objectives: this study aims to evaluate the prevalence of various arrhythmias and other electrocardiographic patterns within the group of individuals with overweight and obesity. Methods: One hundred eighty-one adults (90 females and 91 males) were qualified for inclusion in the experimental group. All participants had a body mass index (BMI) exceeding 25 kg/m2 (98 patients with obesity and 83 with overweight). The mean BMI in the obesity group was 33.6 kg/m2, and all participants had class 1 obesity. The control group comprised 69 individuals (56 females and 13 males) with normal BMI. The basic measurements were performed, and the participants filled out questionnaires describing their health conditions and lifestyles. Each participant underwent an electrocardiographic (ECG) examination and a 24 h Holter ECG examination. Results: In patients with class 1 obesity compared to the control patients, the average numbers of premature ventricular beats (PVBs) and premature supraventricular beats (SPBs) were statistically significantly higher (p = 0.030 and p = 0.042). There was a positive correlation between body weight and PVB (p = 0.028) and between body weight and SPB (p = 0.028). Moreover, BMI and waist circumference were correlated with SPB (p = 0.043 and p = 0.031). In the backward stepwise multivariate regression model considering 24 h Holter ECG monitoring, concerning SPB as the dependent variable, it was observed that BMI (especially obesity class 1), type 2 diabetes, and thyroid disease exhibited the highest regression coefficients. Conclusions: obesity, even in class 1, might be a factor in a more frequent occurrence of abnormalities in electrocardiographic tests.
